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RGT1383

Chemical Structure : RGT1383

CAS No.: 2428641-93-2

RGT1383 (RGT 1383)

Catalog No.: PC-20600Not For Human Use, Lab Use Only.

RGT1383 is a small molecule GLP-1R agonist, RGT1383 is a full agonist in G protein-mediated cAMP signaling with EC50 of 0.2 nM, and a partial agonist in β-arrestin-mediated signaling.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RGT1383 is a small molecule GLP-1R agonist, RGT1383 is a full agonist in G protein-mediated cAMP signaling with EC50 of 0.2 nM, and a partial agonist in β-arrestin-mediated signaling.

Physicochemical Properties

M.Wt 554.58
Formula C30H27FN6O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(C1=CC=C2C(N(C[C@H]3OCC3)C(CN4CC=C(C5=NC(OCC6=CC=C(C#N)C=C6F)=CC=C5)CC4)=N2)=N1)O

References

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