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Chemical Structure : RH1115
Catalog No.: PC-21540Not For Human Use, Lab Use Only.
RH1115 is a small molecule activator and inducer of autophagy targeting Lamin A/C and LAMP1, induces changes to LAMP1 vesicle properties and alters lysosome positioning.
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RH1115 is a small molecule activator and inducer of autophagy targeting Lamin A/C and LAMP1, induces changes to LAMP1 vesicle properties and alters lysosome positioning.
RH1115 significantly increase the puncta/cell count in eGFP-LC3 puncta formation assays with EC50 of 46.2 uM.
RH1115 alters positioning of lysosomes and increases autophagic flux in human iPSC-derived neurons.
| M.Wt | 356.55 | |
| Formula | C23H36N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ryan S Hippman, et al. ACS Chem Neurosci. 2023 Dec 9. doi: 10.1021/acschemneuro.3c00573.
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