Chemical Structure : RI-2
CAS No.: 1417162-36-7
Catalog No.: PC-45083Not For Human Use, Lab Use Only.
RI-2 (RAD51 inhibitor 2) is a reversible RAD51 inhibitor with IC50 of 44 uM in the standard DNA binding assays.
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RI-2 (RAD51 inhibitor 2) is a reversible RAD51 inhibitor with IC50 of 44 uM in the standard DNA binding assays.
RI-2 specifically inhibits HR repair in human cells, sensitize a broad range of immortalized human cells to mitomycin C.
M.Wt | 433.2846 | |
Formula | C21H18Cl2N2O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 15.5 mg/mL |
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Chemical Name/SMILES |
1H-Pyrrole-2,5-dione, 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)- |
1. Budke B, et al. J Med Chem. 2013 Jan 10;56(1):254-63.
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