Chemical Structure : RIPA-56
CAS No.: 1956370-21-0
Catalog No.: PC-42301Not For Human Use, Lab Use Only.
RIPA-56 is a highly potent, selective, stable Receptor-interacting protein 1 (RIPK1) inhibitor with IC50 of 13 nM.
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RIPA-56 is a highly potent, selective, stable Receptor-interacting protein 1 (RIPK1) inhibitor with IC50 of 13 nM.
RIPA-56 shows good selectivity in kinase panel screening, and does not IDO activity ( at >200 uM).
RIPA-56 efficiently protects mice from mTNFα-induced multi-organ damage.
M.Wt | 221.29546 | |
Formula | C13H19NO2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Butanamide, N-hydroxy-2,2-dimethyl-N-(phenylmethyl)- |
1. Ren Y, et al. J Med Chem. 2017 Feb 9;60(3):972-986.
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