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RIPA-56

Chemical Structure : RIPA-56

CAS No.: 1956370-21-0

RIPA-56 (RIPA56;RIPA 56)

Catalog No.: PC-42301Not For Human Use, Lab Use Only.

RIPA-56 is a highly potent, selective, stable Receptor-interacting protein 1 (RIPK1) inhibitor with IC50 of 13 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RIPA-56 is a highly potent, selective, stable Receptor-interacting protein 1 (RIPK1) inhibitor with IC50 of 13 nM.
RIPA-56 shows good selectivity in kinase panel screening, and does not IDO activity ( at >200 uM).
RIPA-56 efficiently protects mice from mTNFα-induced multi-organ damage.

Physicochemical Properties

M.Wt 221.29546
Formula C13H19NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Butanamide, N-hydroxy-2,2-dimethyl-N-(phenylmethyl)-

References

1. Ren Y, et al. J Med Chem. 2017 Feb 9;60(3):972-986.

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