RIPK2 inhibitor 3

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Chemical Structure : RIPK2 inhibitor 3

Catalog No.: PC-49810Not For Human Use, Lab Use Only.

RIPK2 inhibitor 3 is a potent, selective inhibitor of RIP2 kinase (RIPK2), displays equivalent potency to inhibitor RIPK2 inhibitor 3 in biochemical assays, phosphate ester prodrug.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RIPK2 inhibitor 3 is a potent, selective inhibitor of RIP2 kinase (RIPK2), displays equivalent potency to inhibitor RIPK2 inhibitor 3 in biochemical assays, phosphate ester prodrug.
RIPK2 inhibitor 3 has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human IBD explant samples.

Physicochemical Properties

M.Wt	631.64
Formula	C21H28CaN4O10PS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Calcium(I) 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Hydrogen Phosphate Trihydrate

References

1. Pamela A Haile, et al. J Med Chem. 2019 Jul 25;62(14):6482-6494.

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