RL648_81 (RL648-81, RL-81)

Chemical Structure : RL648_81

CAS No.: 1919050-87-5

Catalog No.: PC-27789Not For Human Use, Lab Use Only.

RL648_81 (RL648-81, RL-81) is a potent subtype-selective KCNQ2/3 (Kv7.2/7.3) channel activator with EC50 of 190 nM, >15 times more potent and also more selective than retigabine.

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25 mg	$138	In stock
50 mg	$228	In stock
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Biological Activity

RL648_81 (RL648-81, RL-81) is a potent subtype-selective KCNQ2/3 (Kv7.2/7.3) channel activator with EC50 of 190 nM, >15 times more potent and also more selective than retigabine.

Physicochemical Properties

M.Wt	371.34
Formula	C17H17F4N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl (2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate

References

1. Manoj Kumar, et al. Mol Pharmacol. 2016 Jun;89(6):667-77.

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