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RO6806051

Chemical Structure : RO6806051

CAS No.: 1433901-75-7

RO6806051

Catalog No.: PC-25549Not For Human Use, Lab Use Only.

RO6806051 is a potent, selective, dual fatty acid binding protein 4 and 5 (FABP4 and FABP5) inhibitor with Ki of 11 nM and 86 nM for hFABP4 and hFABP5 respectively, shows good selectivity over FABP3.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RO6806051 is a potent, selective, dual fatty acid binding protein 4 and 5 (FABP4 and FABP5) inhibitor with Ki of 11 nM and 86 nM for hFABP4 and hFABP5 respectively, shows good selectivity over FABP3.

Physicochemical Properties

M.Wt 390.88
Formula C21H19ClN6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Chloro-4-phenyl-2-(piperidin-1-yl)-3-(2H-tetrazol-5-yl)quinoline

References

1. Kühne H, et al. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5092-5097.

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