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RO6889678

Chemical Structure : RO6889678

CAS No.: 1578153-27-1

RO6889678 (RO 6889678)

Catalog No.: PC-62578Not For Human Use, Lab Use Only.

RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.

Physicochemical Properties

M.Wt 494.922
Formula C21H20ClFN4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholine-3-carboxylic acid

References

1. Kratochwil NA, et al. J Pharmacol Exp Ther. 2018 Feb 16. pii: jpet.117.245712.

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