ROMK inhibitor Compound A

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Chemical Structure : ROMK inhibitor Compound A

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Catalog No.: PC-24563Not For Human Use, Lab Use Only.

ROMK inhibitor Compound A is a potent, highly selective inhibitor renal outer medullary potassium (ROMK, Kir1.1) channel with IC50 of 24 nM, displays good selectivity across other ion channel superfamilies.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	432.48
Formula	C23H24N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(2-(4-(2-(4-(1H-tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one

References

1. Maria L Garcia, et al. J Pharmacol Exp Ther. 2014 Jan;348(1):153-64.

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