ROS151 | AChE inhibitor | Probechem Biochemicals

Chemical Structure : ROS151

ROS151 (ROS-151)

Catalog No.: PC-27446Not For Human Use, Lab Use Only.

ROS151 is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 14 nM (hAChE), as well as a chelator of Fe3+ and Cu2+, shows weak activity against eqBChE, hFAAH, hMAO-A and hMAO-B.

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Biological Activity

ROS151 is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 14 nM (hAChE), as well as a chelator of Fe3+ and Cu2+, shows weak activity against eqBChE, hFAAH, hMAO-A and hMAO-B.

Physicochemical Properties

M.Wt	391.36
Formula	C18H18FN3O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((2-(5-Fluoro-2-nitrophenoxy)acetamido)methyl)phenyl dimethylcarbamate

References

1. Leuci R, et al. Bioorg Chem. 2024 Dec;153:107895.

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ROS151 (ROS-151)

Biological Activity

Physicochemical Properties

References

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