Chemical Structure : RP-67580
Catalog No.: PC-70190Not For Human Use, Lab Use Only.
A potent and selective tachykinin NK1 receptor antagonist with Ki of 2.9 nM.
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A potent and selective tachykinin NK1 receptor antagonist with Ki of 2.9 nM; shows no activity ofr NK2 and NK3 (Ki>10 uM); exhibits antinociceptive activity in writhing and formalin paw tests in mice and gerbils.
M.Wt | 438.57 | |
Formula | C29H30N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Rupniak NM, et al. Br J Pharmacol. 1993 Dec;110(4):1607-13.
2. Beaujouan JC, et al. Br J Pharmacol. 1993 Mar;108(3):793-800.
3. Fong TM, et al. J Biol Chem. 1992 Dec 25;267(36):25668-71.
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