Chemical Structure : RS-1
CAS No.: 312756-74-4
Catalog No.: PC-45715Not For Human Use, Lab Use Only.
RS-1 is a homology-directed repair (HDR) enhancer and RAD51 activator, enhances HDR 3- to 6-fold depending on the locus and transfection method.
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RS-1 is a homology-directed repair (HDR) enhancer and RAD51 activator, enhances HDR 3- to 6-fold depending on the locus and transfection method.
RS-1 shows effectivity on improving knock-in rates in both the TALEN- and the CRISPR/Cas9-mediated genome-editing systems.
M.Wt | 524.2256 | |
Formula | C20H16Br2N2O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzamide, 4-bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]- |
1. Song J, et al. Nat Commun. 2016 Jan 28;7:10548.
2. Pinder J, et al.Nucleic Acids Res. 2015 Oct 30;43(19):9379-92.
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