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RSK2 inhibitor M39

Chemical Structure : RSK2 inhibitor M39

CAS No.: 362000-49-5

RSK2 inhibitor M39

Catalog No.: PC-27207Not For Human Use, Lab Use Only.

RSK2 inhibitor M39 is a high affinity, cell-active RSK2 inhibitor with SPR Kd value of 156 nM, inhibits the catalytic activity of RSK2 by suppressing YB1 phosphorylation and shows strong anti-tumor activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RSK2 inhibitor M39 is a high affinity, cell-active RSK2 inhibitor with SPR Kd value of 156 nM, inhibits the catalytic activity of RSK2 by suppressing YB1 phosphorylation and shows strong anti-tumor activity.

Physicochemical Properties

M.Wt 429.50
Formula C22H19N7OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(((1H-benzo[d]imidazol-2-yl)thio)methyl)-2-((4,7-dimethylquinazolin-2-yl)amino)pyrimidin-4(3H)-one

References

1. Feng N, et al. ChemMedChem. 2026 Jun 26;21(12):e70293.

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