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RU-GIRK-1

Chemical Structure : RU-GIRK-1

CAS No.: 879353-60-3

RU-GIRK-1

Catalog No.: PC-70310Not For Human Use, Lab Use Only.

RU-GIRK-1 is a potent GIRK2 inhibitor that inhibits GIRK2-mediated flux with an IC50 of 0.35 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RU-GIRK-1 is a potent GIRK2 inhibitor that inhibits GIRK2-mediated flux with an IC50 of 0.35 uM.
    RU-GIRK-1 inhibits baclofen-stimulated K+ currents in cultured mouse hippocampal neurons.

    Physicochemical Properties

    M.Wt 306.398
    Formula C14H14N2O2S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-((2,3-dihydro-1H-inden-5-yl)thio)pyridine-3-sulfonamide

    References

    1. Su Z, et al. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5748-53.

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