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RWJ-445167

Chemical Structure : RWJ-445167

CAS No.: 226566-43-4

RWJ-445167 (3DP-10017)

Catalog No.: PC-24865Not For Human Use, Lab Use Only.

RWJ-445167 (3DP-10017) is a potent, dual inhibitor of thrombin and factor Xa (FIIa/Xa inhibitor) with Ki of 4.0/230 nM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RWJ-445167 (3DP-10017) is a potent, dual inhibitor of thrombin and factor Xa (FIIa/Xa inhibitor) with Ki of 4.0/230 nM respectively.

Physicochemical Properties

M.Wt 436.49
Formula C18H24N6O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(guanidinooxy)ethyl)-2-(6-methyl-3-((3-methylphenyl)sulfonamido)-2-oxopyridin-1(2H)-yl)acetamide

References

1. Maryanoff BE, et al. Chem Biol Drug Des. 2006 Jul;68(1):29-36.

2. Giardino EC, et al. Blood Coagul Fibrinolysis. 2010 Mar;21(2):128-34.

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