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Chemical Structure : RX 871024
Catalog No.: PC-60559Not For Human Use, Lab Use Only.
RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells.
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RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells.
RX 871024 blocks ATP-dependent K+ channels and membrane depolarization, and activates voltage-dependent Ca2+ channels.
| M.Wt | 297.78 | |
| Formula | C17H15N3 · HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Efanova IB, et al. Diabetes. 1998 Feb;47(2):211-8.
2. Zaitsev SV, et al. Diabetes. 1996 Nov;45(11):1610-8.
3. Mourtada M, et al. Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8.
4. Mourtada M, et al. Br J Pharmacol. 1999 Jul;127(5):1279-87.
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