Chemical Structure : Rabeprazole
CAS No.: 117976-89-3
Catalog No.: PC-24038Not For Human Use, Lab Use Only.
Rabeprazole (LY307640) is a second-generation proton pump inhibitor that irreversibly inactivates gastric H+/K+-ATPase, also is an uridine nucleoside ribohydrolase (UNH) inhibitor with IC50 of 0.3 uM.
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Rabeprazole (LY307640) is a second-generation proton pump inhibitor that irreversibly inactivates gastric H+/K+-ATPase, also is an uridine nucleoside ribohydrolase (UNH) inhibitor with IC50 of 0.3 uM.
Rabeprazole inhibits the phosphorylation of ERK1/2 in the MKN-28 cells.
Rabeprazole attenuates the cell viability of the human gastric cancer cells.
M.Wt | 359.44 | |
Formula | C18H21N3O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-(((4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole |
1. Tara A Shea, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4.
2. Mengli Gu, et al. Oncol Lett. 2014 Oct;8(4):1739-1744.
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