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Chemical Structure : Rac1-IN-6
Catalog No.: PC-61470Not For Human Use, Lab Use Only.
Rac1-IN-6 is a selective small molecule Rac1 inhibitor that blocks Rac1-PAK1 complex formation with IC50 of 88±48 nM.
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Rac1-IN-6 is a selective small molecule Rac1 inhibitor that blocks Rac1-PAK1 complex formation with IC50 of 88±48 nM.
Rac1-IN-6 diminishes the EGF-induced Rac1 activation in CD18/HPAF cells with EC50 of 22.4±3.2 uM, has no inhibitory effect on either Cdc42 or RhoA in CD18/HPAF cells.
Rac1-IN-6 inhibits the proliferation, reduces migration of pancreatic cancer cells.
| M.Wt | 388.485 | |
| Formula | C23H20N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arnst JL, et al. Oncotarget. 2017 May 23;8(21):34586-34600.
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