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Ralaniten

Chemical Structure : Ralaniten

CAS No.: 1203490-23-6

Ralaniten (EPI-002)

Catalog No.: PC-60529Not For Human Use, Lab Use Only.

Ralaniten (EPI-002) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer.

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10 mg $188 In stock
25 mg $298 In stock
50 mg $468 In stock
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Biological Activity

Ralaniten (EPI-002) is a novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer.
AR NTD-targeting agents have the potential to overcome shortcomings of current hormonal therapies by inhibiting all forms of AR-mediated transcriptional activity, and as a result, may affect a broader AR population including mutational and splice variant ARs.

Physicochemical Properties

M.Wt 394.89
Formula C21H27ClO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R)-3-[4-(2-{4-[(2S)-3-chloro- 2-hydroxypropoxy]phenyl}propan-2-yl)phenoxy]propane- 1,2-diol

References

1. Antonarakis ES, et al. Oncologist. 2016 Dec;21(12):1427-1435.

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