Chemical Structure : Raltegravir potassium salt
CAS No.:
871038-72-1
Raltegravir potassium salt
(MK0518 potassium salt, MK-0518 potassium salt)
Catalog No. : PC-42549Not For Human Use, Lab Use Only.
Raltegravir potassium salt (MK-0518) is a potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4254901
Biological Activity
Raltegravir potassium salt (MK-0518) is a potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM.
Physicochemical Properties
M.Wt
482.5067
Formula
C20H20FKN6O5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-, potassium salt(1:1)
References
1. Summa V, et al. J Med Chem. 2008 Sep 25;51(18):5843-55.
2. Malet I, et al. Antimicrob Agents Chemother. 2008 Apr;52(4):1351-8.
3. Cooper DA, et al. N Engl J Med. 2008 Jul 24;359(4):355-65.
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