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Ramoplanin

Chemical Structure : Ramoplanin

CAS No.: 76168-82-6

Ramoplanin (A-16686, MDL 62,198)

Catalog No.: PC-22942Not For Human Use, Lab Use Only.

Ramoplanin (A-16686) is a glycolipodepsipeptide antibiotic with MIC50 of 1.45 ug/mL against methicillin-resistant S. epidermidis (MRSE), shows activity against staphylococci, enterococci and C. difficile.

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Biological Activity

Ramoplanin (A-16686) is a glycolipodepsipeptide antibiotic with MIC50 of 1.45 ug/mL against methicillin-resistant S. epidermidis (MRSE), shows activity against staphylococci, enterococci and C. difficile.

Physicochemical Properties

M.Wt 2254.09
Formula C106H170ClN21O30
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[[(2R)-2-[[(2S)-2-[[2-[[2-[[(2S,3S)-2-[[2-[[(2R)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2R)-2-[[(2R)-2-[[(2R,3S)-2-[[(2R)-5-amino-2-[[(2R)-2-[[4-amino-2-[[(2S)-4-amino-2-[[(2Z,4Z)-octa-2,4-dienoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-2-(4-hydroxycyclohexyl)acetyl]amino]pentanoyl]amino]-3-hydroxybutanoyl]amino]-2-(4-hydroxycyclohexyl)acetyl]amino]-2-(4-hydroxycyclohexyl)acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-2-(4-hydroxycyclohexyl)acetyl]amino]-3-

References

1. O'Hare MD, et al. J Chemother. 1989 Jul;1(4 Suppl):210-1.

2. Biavasco F, et al. Antimicrob Agents Chemother. 1991 Jan;35(1):195-7.

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