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Ranibizumab

Chemical Structure : Ranibizumab

CAS No.:

Ranibizumab (Anti-human VEGFA mAb, human IgG1-Kappa; RG6321)

Catalog No.: PC-Ab1063Not For Human Use, Lab Use Only.

Ranibizumab (Lucentis, RG-6321) is a specific affinity-matured, recombinant, humanized, anti-VEGF antigen-binding antibody fragment (Fab) that binds and neutralizes all the biologically active forms of VEGF-A, an important mediator in the development of choroidal neovascularisation. Ranibizumab was approved by the Food and Drug Administration (FDA) for the treatment of neovascular AMD..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ranibizumab (Lucentis, RG-6321) is a specific affinity-matured, recombinant, humanized, anti-VEGF antigen-binding antibody fragment (Fab) that binds and neutralizes all the biologically active forms of VEGF-A, an important mediator in the development of choroidal neovascularisation. Ranibizumab was approved by the Food and Drug Administration (FDA) for the treatment of neovascular AMD.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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