Chemical Structure : Ranolazine dihydrochloride
CAS No.: 95635-56-6
Catalog No.: PC-45224Not For Human Use, Lab Use Only.
Ranolazine dihydrochloride is an anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models.
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Ranolazine dihydrochloride is an anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models.
Ranolazine dihydrochloride also inhibits cardiac sodium channel Nav1.5, shows antiarrhythmic, antiepileptic, and analgesic effects.
M.Wt | 500.4584 | |
Formula | C24H35Cl2N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, hydrochloride (1:2) |
1. Sokolov S, et al. Front Pharmacol. 2013 Jun 21;4:78.
2. Noble D, et al. Heart. 2006 Jul;92 Suppl 4:iv1-iv5.
3. Wang WQ, et al. J Pharmacol Exp Ther. 2008 Jun;325(3):875-81.
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