Chemical Structure : Rapastinel trifluoroacetate
CAS No.:
1435786-04-1
Rapastinel trifluoroacetate
(GLYX-13, Thr-Pro-Pro-Thr-NH2 TFA)
Catalog No. : PC-22608Not For Human Use, Lab Use Only.
Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2) trifluoroacetateis a tetrapeptide (TPPT-amide) that acts as a NMDA receptor glycine site partial agonist.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2260801
Biological Activity
Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2) trifluoroacetateis a tetrapeptide (TPPT-amide) that acts as a NMDA receptor glycine site partial agonist.
Physicochemical Properties
M.Wt
527.50
Formula
C20H32F3N5O8
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-1-(L-threonyl-L-prolyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
References
1. Moskal JR, et al. Neuropharmacology. 2005 Dec;49(7):1077-87.
2. Zhang XL, et al. Neuropharmacology. 2008 Dec;55(7):1238-50.
3. Burgdorf J, et al. Neurobiol Aging. 2011 Apr;32(4):698-706.
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