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Ravuconazole

Chemical Structure : Ravuconazole

CAS No.: 182760-06-1

Ravuconazole (BMS-207147, ER-30346)

Catalog No.: PC-27942Not For Human Use, Lab Use Only.

Ravuconazole (BMS-207147, ER-30346) is an oral triazole antifungal with broad antifungal spectrum with MIC90 of 0.025 to 0.78 ug/mL, 4 to 32 times more active than itraconazole, fluconazole, and amphotericin B against Candida albicans, Candida parapsilosis, and Candida glabrata.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ravuconazole (BMS-207147, ER-30346) is an oral triazole antifungal with broad antifungal spectrum with MIC90 of 0.025 to 0.78 ug/mL, 4 to 32 times more active than itraconazole, fluconazole, and amphotericin B against Candida albicans, Candida parapsilosis, and Candida glabrata.

Physicochemical Properties

M.Wt 437.47
Formula C22H17F2N5OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(2-((2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)thiazol-4-yl)benzonitrile

References

1. Fung-Tomc JC, et al. Antimicrob Agents Chemother. 1998 Feb;42(2):313-8.

2. Hata K, et al. Antimicrob Agents Chemother. 1996 Oct;40(10):2243-7.

3. Hata K, et al. Antimicrob Agents Chemother. 1996 Oct;40(10):2237-42.

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