Relatlimab
(Anti-human LAG3 mAb, human IgG4 (S228P)-Kappa; BMS-986016)
Catalog No.: PC-Ab1014Not For Human Use, Lab Use Only.
Relatlimab (BMS-986016) is a human IgG4 anti-LAG3 blocking mAb. Combination of LAG-3 with the immunomodulatory drug (IMiD) lenalidomide significantly increased IL-2 production by T cells and antibody-dependent cytotoxicity (ADCC) mediated by NK cells. These datas provide new insights into the potential anti-leukemic effects.
Relatlimab (BMS-986016) is a human IgG4 anti-LAG3 blocking mAb. Combination of LAG-3 with the immunomodulatory drug (IMiD) lenalidomide significantly increased IL-2 production by T cells and antibody-dependent cytotoxicity (ADCC) mediated by NK cells. These datas provide new insights into the potential anti-leukemic effects
Physicochemical Properties
M.Wt
Formula
Human IgG4 (S228P)-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
