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Chemical Structure : Retapamulin
CAS No.: 224452-66-8
Catalog No.: PC-45135Not For Human Use, Lab Use Only.
Retapamulin (SB275833) is an pleuromutilin antibiotic, specifically a protein synthesis inhibitor by interacting on the 50S subunit of the bacterial ribosome, binds to both E. coli and S. aureus ribosomes with Kd of 3 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $98 | In stock | |
| 100 mg | $138 | In stock | |
| 250 mg | $218 | In stock | |
| 1 g | Get quote |
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Retapamulin (SB275833) is an pleuromutilin antibiotic, specifically a protein synthesis inhibitor by interacting on the 50S subunit of the bacterial ribosome, binds to both E. coli and S. aureus ribosomes with Kd of 3 nM.
Retapamulin demonstrates high efficacy against certain Gram-positive bacteria including MRSA.
| M.Wt | 517.7635 | |
| Formula | C30H47NO4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 52 mg/mL |
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| Chemical Name/SMILES |
Acetic acid, 2-[[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester |
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1. Goldstein EJ, et al. Antimicrob Agents Chemother. 2006 Jan;50(1):379-81.
2. Jones RN, et al. Antimicrob Agents Chemother. 2006 Jul;50(7):2583-6.
3. Champney WS, et al. Antimicrob Agents Chemother. 2007 Sep;51(9):3385-7.
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