Revizinone (R80122) | PDE3 inhibitor | Probechem Biochemicals

Chemical Structure : Revizinone

Catalog No.: PC-42211Not For Human Use, Lab Use Only.

Revizinone (R80122) is a potent, selective PDE3 inhibitor with IC50 of 36 nM, displays >20,000-fold selectivity over PDE1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Revizinone (R80122) is a potent, selective PDE3 inhibitor with IC50 of 36 nM, displays >20,000-fold selectivity over PDE1.

M.Wt	459.5402
Formula	C26H29N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 4.6 mg/mL
Chemical Name/SMILES	Acetamide, N-cyclohexyl-N-methyl-2-[[(E)-[phenyl(1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazolin-7-yl)methylene]amino]oxy]-

1. Vandeplassche GM, et al. J Cardiovasc Pharmacol. 1992 May;19(5):714-22.

2. Wilhelm D, et al. J Cardiovasc Pharmacol. 1992;20(5):705-14.

3. de Cheffoy de Courcelles D,, et al. J Pharmacol Exp Ther. 1992 Oct;263(1):6-14.