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Rhamnocitrin

Chemical Structure : Rhamnocitrin

CAS No.: 569-92-6

Rhamnocitrin

Catalog No.: PC-23402Not For Human Use, Lab Use Only.

Rhamnocitrin is a flavonoid with anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity, also shows antiviral activity against influenza virus H3N2 by inhibiting cGAS/STING pathway.

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Biological Activity

Rhamnocitrin is a flavonoid with anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity, also shows antiviral activity against influenza virus H3N2 by inhibiting cGAS/STING pathway.
Rhamnocitrin shows antiviral effect and anti-apoptosis on influenza virus A/Aichi/2/1968 (H3N2) in MDCK cells and A549 cells.
Rhamnocitrin has good binding activity with the target proteins cGAS and STING (Kd=2.6 uM).
Rhamnocitrin could reduce type I IFN and proinflammatory cytokines production by inhibiting the cGAS/STING pathway.

Physicochemical Properties

M.Wt 300.27
Formula C16H12O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one

References

1. Zexing Chen, et al. Sci Rep. 2024 Nov 16;14(1):28287.

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