RhoA-ROCK-IN-1

Chemical Structure : RhoA-ROCK-IN-1

Catalog No.: PC-28588Not For Human Use, Lab Use Only.

RhoA/ROCK-IN-1 (Compound b19) is a small molecule RhoA/ROCK pathway inhibitor, has anti-proliferative activity on A549 cells with IC50 of 4.8 uM, significantly inhibits the proliferation, migration, and invasion of MDA-MB-231 cells and promotes apoptosis.

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Biological Activity

Physicochemical Properties

M.Wt	449.53
Formula	C24H23N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(5-(1-methyl-1H-pyrazol-4-yl)-1,1-dioxidobenzo[b]thiophen-3-yl)(4-phenoxypiperidin-1-yl)methanone

References

1. Jinhao Liang, et al. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2390911.

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RhoA-ROCK-IN-1

Biological Activity

Physicochemical Properties

References

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