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Ribocil-C

Chemical Structure : Ribocil-C

CAS No.: 1825355-56-3

Ribocil-C (Ribocil C)

Catalog No.: PC-45638Not For Human Use, Lab Use Only.

Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli.

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Biological Activity

Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli.
Ribocil-C inhibits dual FMN riboswitches, separately controlling RF biosynthesis and uptake processes essential for MRSA growth and pathogenesis.

Physicochemical Properties

M.Wt 419.5027
Formula C21H21N7OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4(3H)-Pyrimidinone, 2-[(3S)-1-[[1-(2-pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)-

References

1. Wang H, et al. Cell Chem Biol. 2017 May 18;24(5):576-588.e6.

2. Krajewski SS, et al. Cell Chem Biol. 2017 May 18;24(5):535-537.

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