Chemical Structure : Ribocil
CAS No.: 1381289-58-2
Catalog No.: PC-45637Not For Human Use, Lab Use Only.
Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB.
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Ribocil is a synthetic mimic of riboflavin 5’-monophosphate (FMN) that competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB.
Ribocil depletes cellular levels of riboflavin with an IC50 value of 0.3 µM and inhibits E. coli growth with an MIC value of 2 ug/ml.
M.Wt | 382.4826 | |
Formula | C19H22N6OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4(3H)-Pyrimidinone, 2-[1-[[2-(methylamino)-5-pyrimidinyl]methyl]-3-piperidinyl]-6-(2-thienyl)- |
1. Howe JA, et al. Nature. 2015 Oct 29;526(7575):672-7.
2. Hermann T. Nature. 2015 Oct 29;526(7575):650-1.
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