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Chemical Structure : Ridinilazole
CAS No.: 308362-25-6
Catalog No.: PC-22943Not For Human Use, Lab Use Only.
Ridinilazole (SMT19969) is a narrow-spectrum, non-absorbable antimicrobial against Clostridium difficile with MIC of 0.125 to 0.5 ug/ml, MIC90 of 0.25 ug/mL, including ribotype 027 strains.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | $548 | In stock | |
| 100 mg | Get quote |
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Ridinilazole (SMT19969) is a narrow-spectrum, non-absorbable antimicrobial against Clostridium difficile with MIC of 0.125 to 0.5 ug/ml, MIC90 of 0.25 ug/mL, including ribotype 027 strains.
Ridinilazole (SMT19969) is more active against C. difficile isolates than fidaxomicin (range, 0.06 to 1 μg/ml; MIC90, 0.5 μg/ml) and two to six dilutions lower than either vancomycin or metronidazole.
Ridinilazole (SMT19969) is generally less active against Gram-negative anaerobes, especially the Bacteroides fragilis group species, than vancomycin and metronidazole. SMT19969 showed limited activity against other Gram-positive anaerobes, including Bifidobacteria species, Eggerthella lenta, Finegoldia magna, and Peptostreptococcus anaerobius, with MIC90s of >512, >512, 64, and 64 μg/ml, respectively.
| M.Wt | 388.43 | |
| Formula | C24H16N6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,2'-Di(pyridin-4-yl)-1H,1'H-5,5'-bibenzo[d]imidazole |
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1. Sattar A, et al. J Antimicrob Chemother. 2015;70(6):1757-62.
2. Corbett D, et al. J Antimicrob Chemother. 2015;70(6):1751-6.
3. Goldstein EJ, et al. Antimicrob Agents Chemother. 2013 Oct;57(10):4872-6.
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