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Chemical Structure : Rilapladib
CAS No.: 412950-08-4
Catalog No.: PC-70212Not For Human Use, Lab Use Only.
Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM.
Rilapladib (SB-659032, SB659032) shows potential for the treatment of Alzheimer's disease and atherosclerosis.
| M.Wt | 735.814 | |
| Formula | C40H38F5N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(2-((2,3-difluorobenzyl)thio)-4-oxoquinolin-1(4H)-yl)-N-(1-(2-methoxyethyl)piperidin-4-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide |
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1. Tawakol A, et al. J Am Coll Cardiol. 2014 Jan 7-14;63(1):86-8.
2. Shaddinger BC, et al. PLoS One. 2014 Jan 27;9(1):e83094.
3. Wilensky RL, et al. Curr Opin Lipidol. 2009 Oct;20(5):415-20.
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