Rilapladib (SB-659032, SB659032)

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Phospholipase-Rilapladib

Chemical Structure : Rilapladib

CAS No.: 412950-08-4

Catalog No.: PC-70212Not For Human Use, Lab Use Only.

Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis..

Packing	Price	Stock
5 mg	$148	In stock
10 mg	$238	In stock
25 mg	$398	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM.
Rilapladib (SB-659032, SB659032) shows potential for the treatment of Alzheimer's disease and atherosclerosis.

Physicochemical Properties

M.Wt	735.814
Formula	C40H38F5N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-((2,3-difluorobenzyl)thio)-4-oxoquinolin-1(4H)-yl)-N-(1-(2-methoxyethyl)piperidin-4-yl)-N-((4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methyl)acetamide

References

1. Tawakol A, et al. J Am Coll Cardiol. 2014 Jan 7-14;63(1):86-8.

2. Shaddinger BC, et al. PLoS One. 2014 Jan 27;9(1):e83094.

3. Wilensky RL, et al. Curr Opin Lipidol. 2009 Oct;20(5):415-20.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com