Catalog No.: PC-24489Not For Human Use, Lab Use Only.
Riluzole is an anticonvulsant agent and N-methyl-D-aspartate (NMDA) glutamate receptor blocker, also is a TPC2 activator, also inhibits Kv4.2, Kv4.2/DPP6, and Kv4.2/KChIP2c channels in a voltage-independent manner.
Riluzole is an anticonvulsant agent and N-methyl-D-aspartate (NMDA) glutamate receptor blocker, also is a TPC2 activator, also inhibits Kv4.2, Kv4.2/DPP6, and Kv4.2/KChIP2c channels in a voltage-independent manner.
Riluzole also binds to the C-terminal domain of SARS-CoV-2 nucleocapsid protein and has antiviral activity.
Physicochemical Properties
M.Wt
234.20
Formula
C8H5F3N2OS
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
6-(Trifluoromethoxy)benzo[d]thiazol-2-amine
References
1. He Y, et al. Neuropharmacology. 2002 Feb;42(2):199-209.
2. Delgado-Ramírez M, et al. Eur J Pharmacol. 2025 Jan 5;986:177146.
3. Márquez-Moñino MÁ, et al. Structure. 2025 Jan 2;33(1):39-50.e6.
