Catalog No.: PC-20917Not For Human Use, Lab Use Only.
Riociguat (BAY 63-2521) is a potent, orally active stimulator of soluble guanylate cyclase (sGC) with MEC of 0.03 uM for achieve threefold stimulation of cGMP formation in recombinant sGC-overexpressing cell line.
Riociguat (BAY 63-2521) is a potent, orally active stimulator of soluble guanylate cyclase (sGC) with MEC of 0.03 uM for achieve threefold stimulation of cGMP formation in recombinant sGC-overexpressing cell line. Riociguat (BAY 63-2521) inhibits the contraction of rabbit aorta with IC50 of 120 nM. Riociguat (BAY 63-2521) exerts strong effects on pulmonary hemodynamics and exercise capacity in patients with pulmonary hypertension (PH).
