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Ritonavir

Chemical Structure : Ritonavir

CAS No.: 155213-67-5

Ritonavir (A-84538, ABT-538)

Catalog No.: PC-46010Not For Human Use, Lab Use Only.

Ritonavir (A-84538, ABT-538) is a potent HIV protease inhibitor for treatment of HIV-1 infection, also inhibits SARS-CoV 3CLpro with IC50 of 1.61 uM.

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Biological Activity

Ritonavir (A-84538, ABT-538) is a potent HIV protease inhibitor for treatment of HIV-1 infection, also inhibits SARS-CoV 3CLpro with IC50 of 1.61 uM.

Physicochemical Properties

M.Wt 720.9442
Formula C37H48N6O5S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO; H2O:< 0.1 mg/mL

Chemical Name/SMILES

2,7,10,12-Tetraazatridecanoic acid, 4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3S,4S,6S,9S)-

References

1. Eagling VA, et al. Br J Clin Pharmacol, 1997, 44(2), 190-194.

2. Zeldin RK, et al. J Antimicrob Chemother. 2004 Jan;53(1):4-9.

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