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Rizatriptan benzoate

Chemical Structure : Rizatriptan benzoate

CAS No.: 145202-66-0

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Rizatriptan benzoate (MK-0462, MK-462)

Catalog No.: PC-25709Not For Human Use, Lab Use Only.

Rizatriptan benzoate (MK-462, MK-0462) is a potent and selective 5-HT1D receptor agonist with binding pIC50 of 7.3, shows little to no affinity for 5-HT1A, 5-HT2C, 5-HT2A and 5-HT3 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Rizatriptan benzoate (MK-462, MK-0462) is a potent and selective 5-HT1D receptor agonist with binding pIC50 of 7.3, shows little to no affinity for 5-HT1A, 5-HT2C, 5-HT2A and 5-HT3 receptors.

Physicochemical Properties

M.Wt 391.48
Formula C22H25N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1H-indol-3-yl)-N,N-dimethylethan-1-amine benzoate

References

1. L J Street , et al. J Med Chem. 1995 May 12;38(10):1799-810.

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