Chemical Structure : Ro 08-2750
CAS No.:
37854-59-4
Ro 08-2750
(Ro 082750)
Catalog No. : PC-61912Not For Human Use, Lab Use Only.
Ro 08-2750 (Ro 082750) is a potent, selective, non-peptide nerve growth factor (NGF) inhibitor that binds to NGF dimer with Kd of 1 uM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6191201
Biological Activity
Ro 08-2750 (Ro 082750) is a potent, selective, non-peptide nerve growth factor (NGF ) inhibitor that binds to NGF dimer with Kd of 1 uM.
Physicochemical Properties
M.Wt
270.24
Formula
C13H10N4O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde
References
1. Niederhauser O, et al. J Neurosci Res. 2000 Aug 1;61(3):263-72.
2. Eibl JK, et al. Eur J Pharmacol. 2013 May 15;708(1-3):30-7.
3. Chakravarthy R, et al. Biochem Biophys Res Commun. 2016 Sep 30;478(4):1541-7.
4. Li B, et al. Oncotarget. 2016 Dec 6;7(49):81026-81048.
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