Chemical Structure : Ro106-9920
Catalog No.: PC-24857Not For Human Use, Lab Use Only.
Ro106-9920 is a specific small molecule inhibitor of NF-kappa B-dependent cytokine expression with IC50 of <1 uM in human PBMSc, selectively inhibits IkappaB(alpha)(ee) ubiquitination with with iC50 of 2.3 uM.
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Ro106-9920 is a specific small molecule inhibitor of NF-kappa B-dependent cytokine expression with IC50 of <1 uM in human PBMSc, selectively inhibits IkappaB(alpha)(ee) ubiquitination with with iC50 of 2.3 uM.
Ro106-9920 is selective for IkappaB(alpha)(ee) ubiquitination over the ubiquitin-activating enzyme (E1), E2UBCH7, nonspecific ubiquitination of cellular proteins, and 97 other molecular targets.
M.Wt | 245.26 | |
Formula | C10H7N5OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Swinney DC, et al. J Biol Chem. 2002 Jun 28;277(26):23573-81.
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