Chemical Structure : Ro 41-1049 hydrochloride
CAS No.: 127917-66-2
Catalog No.: PC-42039Not For Human Use, Lab Use Only.
Ro 41-1049 hydrochloride is a potent, selective, reversible, orally active monoamine oxidase A (MAO-A) inhibitor with Kd of 16.5 nM.
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Ro 41-1049 hydrochloride is a potent, selective, reversible, orally active monoamine oxidase A (MAO-A) inhibitor with Kd of 16.5 nM.
Ro 41-1049 produces a concentration-dependent increase of newly formed dopamine and reduces DOPAC formation in vitro (50-100 nM),
M.Wt | 301.7675 | |
Formula | C12H13ClFN3OS | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 32 mg/mL |
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Chemical Name/SMILES |
4-Thiazolecarboxamide, N-(2-aminoethyl)-5-(3-fluorophenyl)-, hydrochloride (1:1) |
1. Fernandes MH, et al. J Pharmacol Exp Ther. 1990 Dec;255(3):1309-13.
2. Saura J, et al. J Neurosci. 1992 May;12(5):1977-99.
3. Pestana M, et al. Br J Pharmacol. 1994 Dec;113(4):1269-74.
4. Cesura AM, et al. Mol Pharmacol. 1990 Mar;37(3):358-66.
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