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Rohinitib

Chemical Structure : Rohinitib

CAS No.: 1139253-73-8

Rohinitib

Catalog No.: PC-72482Not For Human Use, Lab Use Only.

Rohinitib is a potent and specific inhibitor of eIF4A1, inhibits growth and survival of AML cells especially cells with FLT3-ITD.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Rohinitib is a potent and specific inhibitor of eIF4A1, inhibits growth and survival of AML cells especially cells with FLT3-ITD.

    Physicochemical Properties

    M.Wt 521.56
    Formula C29H31NO8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-N,N,6,8-tetramethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxamide

    References

    1. Nishida Y, et al. Leukemia. 2021 Sep;35(9):2469-2481.

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