Rongliflozin L-pyroglutamic acid

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Chemical Structure : Rongliflozin L-pyroglutamic acid

Catalog No.: PC-24164Not For Human Use, Lab Use Only.

Rongliflozin L-pyroglutamic acid (Olorigliflozin, DJT1116PG) is a potent, selective inhibitor of sodium-glucose co-transporter-2 (SGLT2), selectively inhibits renal glucose reabsorption, has an insulin-independent potential for type 2 diabetes mellitus.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	580.03
Formula	C28H34ClNO10
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-oxopyrrolidine-2-carboxylic acid compound with (1R,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-((R)-1-hydroxyethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1)

References

1. Zhang H, et al. Diabetes Obes Metab. 2020 Feb;22(2):191-202.

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