S. aureus ClpC activator Cpd-8

Chemical Structure : S. aureus ClpC activator Cpd-8

Catalog No.: PC-28531Not For Human Use, Lab Use Only.

S. aureus ClpC activator Cpd-8 is a small-molecule activator of the Staphylococcus aureus ClpC/ClpP AAA+ protease with EC50 of 12 uM, binds to ClpC N-terminal domain (NTD), induces ClpC/ClpP-independent toxicity in Staphylococcus aureus.

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Biological Activity

Physicochemical Properties

M.Wt	645.71
Formula	C30H27N7O6S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(6-((2-(3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-2-oxoethyl)thio)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)benzenesulfonamide

References

1. Jenne T, et al. iScience. 2026 Sep 22;29(10):117738.

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S. aureus ClpC activator Cpd-8

Biological Activity

Physicochemical Properties

References

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