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Chemical Structure : S.aureus sortase inhibitor 6e
Catalog No.: PC-70327Not For Human Use, Lab Use Only.
Sortase-IN-6e is a small molecule inhibitor of Staphylococcus aureus sortase with IC50 of 9.3 uM.
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Sortase-IN-6e is a small molecule inhibitor of Staphylococcus aureus sortase with IC50 of 9.3 uM.
Sortase-IN-6e blocks P2 precursor cleavage by sortase A with IC50 of 68.7 uM in staphylococci.
Sortase-IN-6e does not affect in vitro staphylococcal growth yet protect mice against lethal S. aureus bacteremia.
| M.Wt | 381.36 | |
| Formula | C14H8N5NaO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhang J, et al. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22.
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