Chemical Structure : S119-8
CAS No.: 443639-96-1
Catalog No.: PC-35387Not For Human Use, Lab Use Only.
S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM).
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S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM); also shows activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus, does not inhibit a non-influenza virus, VSV; exhibits synergistic combined with in vitro viral inhibition assays.
M.Wt | 344.458 | |
Formula | C23H24N2O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzamide, 4-(1,1-dimethylethyl)-N-[4-(phenylamino)phenyl]- |
1. White KM, et al. ACS Infect Dis. 2018 Feb 9;4(2):146-157.
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