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S1P5-IN-15

Chemical Structure : S1P5-IN-15

CAS No.: 1621065-22-2

S1P5-IN-15

Catalog No.: PC-73187Not For Human Use, Lab Use Only.

S1P5-IN-15 is a potent, selective, orally active and brain-penetrant S1P5 antagonist with IC50 of 0.1 nM, no effect on S1P1-4.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    S1P5-IN-15 is a potent, selective, orally active and brain-penetrant S1P5 antagonist with IC50 of 0.1 nM, no effect on S1P1-4.

    Physicochemical Properties

    M.Wt 437.624
    Formula C28H39NO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-((2-(((1r,4r)-4-(tert-butyl)cyclohexyl)oxy)-4-methylnaphthalen-1-yl)methyl)piperidine-4-carboxylic acid

    References

    1. ACS Medicinal Chemistry Letters 2021, 12, 3, 351-355

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