Chemical Structure : S 38093
CAS No.: 1222097-72-4
Catalog No.: PC-60377Not For Human Use, Lab Use Only.
S 38093 is a brain-penetrant H3 receptor antagonist/inverse agonist that shows procognitive properties in vivo.
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S 38093 is a brain-penetrant H3 receptor antagonist/inverse agonist that shows procognitive properties in vivo.
S 38093 induces synergistic memory-enhancing effect in mice combined with Donepezil.
S 38093 induces a reversal of age-dependent effects on hippocampal BDNF-IX, BDNF-IV and BDNF-I transcripts and increases vascular endothelial growth factor (VEGF) expression, increases adult hippocampal neurogenesis in vivo.
M.Wt | 324.85 | |
Formula | C17H25ClN2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(3-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)propoxy)benzamide hydrochloride |
1. Panayi F, et al. Eur J Pharmacol. 2017 May 15;803:1-10.
2. Sors A, et al. Eur J Pharmacol. 2017 May 15;803:11-23.
3. Guilloux JP, et al. Sci Rep. 2017 Feb 20;7:42946.
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