Catalog No.: PC-62347Not For Human Use, Lab Use Only.
S3I-M2001 (Bromohydroxyacetone phosphate) is an oxazole-based peptidomimetic of the STAT3 SH2 domain-binding phosphotyrosine peptide that selectively disrupts active STAT3:STAT3 dimers.
S3I-M2001 (Bromohydroxyacetone phosphate) is an oxazole-based peptidomimetic of the STAT3 SH2 domain-binding phosphotyrosine peptide that selectively disrupts active STAT3:STAT3 dimers.
S3I-M2001 inhibits Stat3-dependent transcriptional regulation of tumor survival genes, such as Bcl-xL.
S3I-M2001 suppresses Stat3-dependent malignant transformation, survival, and migration and invasion of mouse and human cancer cells harboring persistently activated Stat3。
S3I-M2001 inhibits growth of human breast tumor xenografts.
