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Chemical Structure : SAMT-247
Catalog No.: PC-62191Not For Human Use, Lab Use Only.
SAMT-247 is a potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.
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SAMT-247 is a potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.
SAMT-247 promotes covalent acetylation of Gag intracellularly, thereby blocking Gag processing and reducing infectivity.
| M.Wt | 266.32 | |
| Formula | C12H14N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Miller Jenkins LM, et al. Nat Chem Biol. 2010 Dec;6(12):887-9.
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