SAMT-247 |CAS:850715-59-2 Probechem Biochemicals

Chemical Structure : SAMT-247

SAMT-247 (SAMT247)

Catalog No.: PC-62191Not For Human Use, Lab Use Only.

SAMT-247 is a potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.

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Biological Activity

SAMT-247 is a potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.
SAMT-247 promotes covalent acetylation of Gag intracellularly, thereby blocking Gag processing and reducing infectivity.

Physicochemical Properties

M.Wt	266.32
Formula	C12H14N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanethioic acid,S-[2-[[(3-amino-3-oxopropyl)amino]carbonyl]phenyl] ester

References

1. Miller Jenkins LM, et al. Nat Chem Biol. 2010 Dec;6(12):887-9.

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SAMT-247 (SAMT247)

Biological Activity

Physicochemical Properties

References

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